Conjugated Equine Estrogens and Global Cognitive Function in Postmenopausal Women<SUBTITLE>Women's Health Initiative Memory Study</SUBTITLE>
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چکیده
منابع مشابه
Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study.
CONTEXT The Women's Health Initiative Memory Study (WHIMS) previously reported that estrogen plus progestin therapy does not protect cognition among women aged 65 years or older. The effect of estrogen-alone therapy, also evaluated in WHIMS, on cognition has not been established for this population. OBJECTIVES To determine whether conjugated equine estrogen (CEE) alters global cognitive funct...
متن کاملConjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study.
CONTEXT The Women's Health Initiative Memory Study (WHIMS) previously found increased risk for dementia and no effect on mild cognitive impairment (MCI) in women treated with conjugated equine estrogens (CEE) plus medroxyprogesterone acetate (MPA). OBJECTIVE To determine the effects of CEE alone and CEE plus MPA on incidence of probable dementia and MCI in older women. DESIGN, SETTING, AND ...
متن کاملConjugated equine estrogens and colorectal cancer incidence and survival: the Women's Health Initiative randomized clinical trial.
BACKGROUND In separate Women's Health Initiative randomized trials, combined hormone therapy with estrogen plus progestin reduced colorectal cancer incidence but estrogen alone in women with hysterectomy did not. We now analyze features of the colorectal cancers that developed and examine the survival of women following colorectal cancer diagnosis in the latter trial. PARTICIPANTS AND METHODS...
متن کاملConjugated equine estrogens and coronary heart disease: the Women's Health Initiative.
BACKGROUND In recent randomized trials, conjugated equine estrogens (CEE) with continuous medroxyprogesterone acetate provided no protection against coronary heart disease in postmenopausal women and may have increased cardiac risk. These trials did not address the role of unopposed estrogen for coronary protection. METHODS A total of 10 739 women aged 50 to 79 years at baseline (mean age, 63...
متن کاملEffects of conjugated equine estrogens on breast cancer and mammography screening in postmenopausal women with hysterectomy.
CONTEXT The Women's Health Initiative Estrogen-Aone trial comparing conjugated equine estrogens (CEE) with placebo was stopped early because of an increased stroke incidence and no reduction in risk of coronary heart disease. Preliminary results suggesting possible reduction in breast cancers warranted more detailed analysis. OBJECTIVE To determine the effects of CEE on breast cancers and mam...
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ژورنال
عنوان ژورنال: JAMA
سال: 2004
ISSN: 0098-7484
DOI: 10.1001/jama.291.24.2959